This research primarily focusing on the continuity of production, survival and access related to indigenous methodologies through the use of virtual reality, serious gaming technologies and affordances. Specifically, the aim is to investigate Human Computer Interaction ( HCI) strategies in the context of folklore medicines such as Greek/Unani medicinal system. The research aims at exploring the interpretative, subjective, and phenomenological analysis of the Greek/Unani medicinal system, entrenched in the Middle Eastern and sub continental regions. By articulating the relationships between traditional Unani and virtual reality-based diagnostic processes, the research challenge is to categorize the human personalities and associated temperaments in a responsive digital environment. Through 'Material Objects' and 'Complex Systems' design, the proposed prototype or research stimulus in the form of virtual reality based head-mounted display system aims at reinforcing the re-enactment of intangible heritage. It does this through revitalizing the dying art of traditional diagnosing methodology from the old GreekiUnani medicinal ideology. Drawing on theoretical discussion such as 'Design as a Propositional Activity' and 'Designed Experience', it is intended to fabricate and deploy a virtual reality based prototype inside the traditional GreekiUnani clinic for the evaluation of patients' personality and temperament.